Proparacaine Hydrochloride - CAS# 5875-06-9 cylate JHU 37160 inhibits locomotor activity

JHU 37160 inhibits locomotor activity in mice expressing hM3Dq and hM4Di in D1-expressing neurons

CAS Number: 482-25-7

Epub 2012 Oct 24

Exatecan Mesylate (34 nM) stabilizes DNA-TopoI complexes in PC-6 and PC-6/SN2-5 cells

Smiles: CC(C)(C#N)C1C=C(CN2C=NC=N2)C=C(C=1)C(C)(C)C#N

Proparacaine Hydrochloride - CAS# 5875-06-9 cylate JHU 37160 inhibits locomotor activityProparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property. It is used as a topical ophthalmic anesthetic. Proparacaine hydrochloride stabilizes the neuronal membrane by binding to and inhibiting voltage gated sodium channels, thereby inhibiting sodium ion influx required for the initiation and conduction of impulses within the neuronal cell, and resulting in a loss of sensation.