AMG-Tie2-1 622C-1215 Chemical Name: N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide

Chemical Name: N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide

Neurodazine

Ropivacain is a potent sodium channel blocker and acts as a local anesthetic agent

JNK1 and GSK3 (IC50 > 16 μM)

Smiles: CC1C=CC(CC[C@@H](C)[C@H](O)[C@H](C)C(=O)[C@H](CC)[C@H]2O[C@](C[C@@H]2C)(CC)[C@H]2CC[C@](O)(CC)[C@H](C)O2)=C(C=1O)C(O)=O

AMG-Tie2-1 622C-1215 Chemical Name: N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamideAMG Tie2 1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) with an IC50 of 1 nM. AMG Tie2 1 is a VEGFR2 inhibitor with an IC50 of 3 nM. Product information CAS Number: 870223 96 4 Molecular Weight: 479. 45 Formula: C25H20F3N5O2 Chemical Name: 4 methyl 3 ({3 [2 (methylamino)pyrimidin 4 yl]pyridin 2 yl}oxy) N [3 (trifluoromethyl)phenyl]benzamide Smiles: CC1=CC=C(C=C1OC1=NC=CC=C1C1=CC=NC(NC)=N1)C(=O)NC1=CC(=CC=C1)C(F)(F)F InChiKey: