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The trypanosomal pyruvate carrier is found to be rather insensitive to inhibition by alpha-cyano-4-hydroxycinnamate (Ki=17 mM) but can be completely blocked by UK-5099 (Ki=49 microM)
(-)-α-Pinene is a monoterpene and shows sleep enhancing property through a direct binding to GABAA-benzodiazepine (BZD) receptors by acting as a partial modulator at the BZD binding site
Chemical Name: 1-hydroxypropane-1
InChiKey: JKGIMVBQKSRTGX-VKAVYKQESA-N
The "di" prefix in the common name arises because the formation of the HPO42– anion involves the removal of two protons from phosphoric acid
7-Hydroxymethotrexate Dihydroxybenzoic acid-d3 The trypanosomal pyruvate carrier is7 Hydroxymethotrexate is a major metabolite of Methotrexate (MTX; HY 14519). Methotrexate, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Product information CAS Number: 5939 37 7 Molecular Weight: 470. 44 Formula: C20H22N8O6 Chemical Name: (2S) 2 [(4 {[(2,4 diamino 7 oxo 7,8 dihydropteridin 6