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In a 9L rat glioma (9L-V6R) rat model
CAS Number: 486-35-1
InChi: InChI=1S/C63H98N18O13S/c1-37(2)33-45(57(89)74-41(53(68)85)27-32-95-3)73-52(84)36-72-54(86)46(34-38-15-6-4-7-16-38)78-58(90)47(35-39-17-8-5-9-18-39)79-56(88)42(23-25-50(66)82)75-55(87)43(24-26-51(67)83)76-59(91)49-22-14-31-81(49)62(94)44(20-10-11-28-64)77-60(92)48-21-13-30-80(48)61(93)40(65)19-12-29-71-63(69)70/h4-9
Phase I safety
is the most potent and selective Lysine Specific Demethylase-1 (LSD1) inhibitor reported to date
Dydrogesterone at (LY450139) In a 9L rat gliomaAmetantrone (AM) is a synthetic 9,10 anthracenedione bearing two (hydroxyethylamino)ethylamino residues at positions 1 and 4; along with other anthraquinones and anthracyclines, it shares a polycyclic intercalating moiety and charged side chains that stabilize DNA binding. Ametantrone is the second anthracene derivative to enter clinical trials. Product information CAS Number: 152 62 5 Molecular Weight: 312. 45 Formula: C21H28O2 Synonym: Duphaston