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GSK2795039 in-3 a fluorinated pyrimidine analogue

SKU: 66551267370

4.3
USD196.35 USD234.35

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Description

a fluorinated pyrimidine analogue

¹⁰]tetradec-12-en-8-one

4 μM) with respect to Shh and as a noncompetitive inhibitor (Ki = 6

ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20

Shapiro AM

GSK2795039 in-3 a fluorinated pyrimidine analogueGSK2795039 is a NADPH oxidase 2 (NOX2) inhibitor with a mean pIC50 of 6 in different cell free assays. GSK2795039 inhibits reactive oxygen species (ROS) production and NADPH consumption. GSK2795039 reduces apoptosis. Product information CAS Number: 1415925 18 6 Molecular Weight: 450. 56 Formula: C23H26N6O2S Chemical Name: 1 methyl N [3 (1 methyl 2, 3 dihydro 1H indol 6 yl) 1 (propan 2 yl) 1H pyrrolo[2, 3 b]pyridin 4 yl] 1H pyrazole 3 sulfonamide

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