BMS-345541 hydrochloride Size:Solid 2 mg InChi: InChI=1S/C21H19NO5/c23-18-7-3-1-5-14(18)12-22(13-15-6-2-4-8-19(15)24)16-9-10-20(25)17(11-16)21(26)27/h1-11

Name: BMS-345541 hydrochloride Size:Solid 2 mg InChi: InChI=1S/C21H19NO5/c23-18-7-3-1-5-14(18)12-22(13-15-6-2-4-8-19(15)24)16-9-10-20(25)17(11-16)21(26)27/h1-11
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SKU: 65789192937
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SKU: 65789192937

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Description

InChi: InChI=1S/C21H19NO5/c23-18-7-3-1-5-14(18)12-22(13-15-6-2-4-8-19(15)24)16-9-10-20(25)17(11-16)21(26)27/h1-11

Chemical Name: (E)-2-(4-carbamimidoyl-2

929007-72-7

Molecular Weight: 342

Balicatib(AAE-581)

BMS-345541 hydrochloride Size:Solid 2 mg InChi: InChI=1S/C21H19NO5/c23-18-7-3-1-5-14(18)12-22(13-15-6-2-4-8-19(15)24)16-9-10-20(25)17(11-16)21(26)27/h1-11BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0. 3 and 4. 0 M for IKK and IKK respectively). It attenuates LPS induced cytokine production in vitro and blocks NFB dependent transcription in mice. BMS 345541 also suppresses joint destruction in a mouse model of arthritis. Product information CAS Number: 547757 23 3 Molecular Weight: 291. 78 Formula: C14H18ClN5 Synonym: BMS345541 hydrochloride BMS 345541 hydrochloride BMS 345541

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