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Crizotinib Hydrochloride - CAS# 1415560-69-8 Size:Solid 2 mg is a non-nucleoside reverse transcriptase

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Description

is a non-nucleoside reverse transcriptase inhibitor potentially for the treatment of HIV infection

InChi: InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8

PubMed PMID: 25088224

Arctiin is a lignan found in many plants of the Asteraceae family

NHE-mediated pH(i) recovery was unaffected by 30 microM S0859

Crizotinib Hydrochloride - CAS# 1415560-69-8 Size:Solid 2 mg is a non-nucleoside reverse transcriptaseCrizotinib (PF 02341066) hydrochloride (Xalkori) inhibits tyrosine phosphorylation of c Met and nucleophosmin (NPM) anaplastic lymphoma kinase (ALK) with IC50 of of 11 nM and 24 nM in cell based assays, respectively. Crizotinib hydrochloride is also a potent ROS1 inhibitor with Ki less than 0. 025 nM. Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines. Product information CAS Number: 1415560 69 8

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