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CAN-15-0817
InChi: InChI=1S/C15H13N3O3S/c1-21-15(19)18-14-16-12-8-7-11(9-13(12)17-14)22(20)10-5-3-2-4-6-10/h2-9H
CAS Number: 872363-17-2
Thalidomide-PEG2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology
(R)-Thalidomide has sedative properties
TyK2-IN-2 aminomethyl CAN-15-0817TyK2 IN 2 (Compoud 18) is a potent and selective TYK2 inhibitor with IC50s of 7 nM, 0. 1 M and 0. 05 M for TYK2 JH2, IL 23 and IFN, respectively. TyK2 IN 2 also inhibits phosphodiesterase 4 (PDE4) with an IC50 of 62 nM. TyK2 IN 2 can be used for the research of inflammatory and autoimmune diseases. Product information CAS Number: 2098466 94 3 Molecular Weight: 310. 35 Formula: C16H18N6O Chemical Name: 6 [(3,5 dimethylphenyl)amino] 8