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Connolly PJ
Smiles: CC1=C(C2C=CC(Cl)=CC=2)N(N=C1C(=O)NN1CCCCC1)C1=CC=C(Cl)C=C1Cl
Formula: C76H106F2N12O20S2
11-pentaen-3-yl}hexanamido)phenyl]arsonous acid
Smiles: CC(O)C(NC(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)CN)C(=O)NC(CO)C(=O)NC(CO)C(=O)NC(CC1C=CC=CC=1)C(=O)NC(C)C(=O)NC(CCC(O)=O)C(=O)NCC(O)=O
BMS 961 Size:Contact [email protected] for quotation Connolly PJBMS961 is a potent and selective retinoic acid receptor gamma (RAR) agonist with IC50 values of 30 nM. RAR belongs to the family of nuclear receptors which regulates transcription. RAR mediates the anti proliferative and apoptotic effects of retinoids in cancer cells such as neuroblastoma cells. RAR is the principal receptor that regulates RA mediated growth arrest in keratinocytes. In vitro, application of BMS961on mouse ear skin was found to cause a