Poloxamer 407 enosine-5'-monophosphate CN([C@@H](CC(C)C)C(=O)NCC[C@H](NC(=O)[C@@H]1CCCN1S(=O)(=O)C1=CC(Cl)=CC(Cl)=C1)C(O)=O)C(=O)CC1C=CC(=CC=1)NC(=O)NC1=CC=CC=C1C

CN([C@@H](CC(C)C)C(=O)NCC[C@H](NC(=O)[C@@H]1CCCN1S(=O)(=O)C1=CC(Cl)=CC(Cl)=C1)C(O)=O)C(=O)CC1C=CC(=CC=1)NC(=O)NC1=CC=CC=C1C

4 nM for PP1 and PP2A

iv) has a T1/2 of 2

Smiles: CC1=CN=CC(CN2CCC(CC2)=C2C3=NC=CC=C3CCC3=CC(Cl)=CC=C32)=C1

Formula: C10H12ClN3

Poloxamer 407 enosine-5'-monophosphate CN([C@@H](CC(C)C)C(=O)NCC[C@H](NC(=O)[C@@H]1CCCN1S(=O)(=O)C1=CC(Cl)=CC(Cl)=C1)C(O)=O)C(=O)CC1C=CC(=CC=1)NC(=O)NC1=CC=CC=C1CPoloxamer 407 is a nonionic surfactant that is 100% active and relatively non toxic to cells at low concentrations, and frequently used with dye AM esters such as Indo 1 AM, Fura 2 AM, Calcein AM, Fluo 3 AM, Fluo 4 AM, Quest Fluo 8 AM and Quest Rhod 4 AM, etc. to improve their water solubility. Product information CAS Number: 9003 11 6 Technical Data Appearance: Solid Power Purity: 98% (or refer to the Certificate of Analysis) Solubility: H2O : 110 mg