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PF-915275 Catalog No.:M19929-C InChi: InChI=1S/C25H25Cl2N7O

SKU: 6076085342

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Description

InChi: InChI=1S/C25H25Cl2N7O

CAS Number: 380917-97-5

the ΔTm/mod is -0

Pro-caspase-9 cleavage

PubMed PMID: 24166903

PF-915275 Catalog No.:M19929-C InChi: InChI=1S/C25H25Cl2N7OPF 915275 is a potent, selective and orally active human 11 hydroxysteroid dehydrogenase type 1 (11HSD1) inhibitor with a Ki of 2. 3 nM and an EC50 of 15 nM (in HEK293 cells). The dose dependent effect of PF 915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively. Product information CAS Number: 857290 04 1 Molecular Weight: 350. 39 Formula: C18H14N4O2S Chemical Name: N (6

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