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gov/books/NBK533338/ PubMed PMID: 30457786
Flavopiridol also potently inhibits the activity of Glycogen synthase kinase-3 (GSK-3) with an IC50 of 280 nm
9 mg/kg per day for 14 days
it binds to and stabilizes tubulin
Int J Physiol Pathophysiol Pharmacol
Lenvatinib - CAS# 417716-92-8 Catalog No.:M8564-10 gov/books/NBK533338/ PubMed PMID: 30457786Lenvatinib, also known as E7080, is a synthetic, orally available inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR FLK 1) tyrosine kinase with potential antineoplastic activity. E7080 blocks VEGFR2 activation by VEGF, resulting in inhibition of the VEGF receptor signal transduction pathway, decreased vascular endothelial cell migration and proliferation, and vascular endothelial cell apoptosis. Product information
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