suggesting that AMG 337 has the preclinical attributes required to test the role of MET in human cancer
InChiKey: ACEWLPOYLGNNHV-UHFFFAOYSA-N
a natural triterpenoid saponin isolated from herb
Chebulinic acid attenuates glutamate-induced HT22 cell death by inhibiting oxidative stress
Smiles: CC1=CC2=CC(=N1)C1C=NN(C)C=1OCCC[C@@H](C)CN1C(NC3=CC=C(CN4CCN(C)CC4)C=C13)=NC2=O |t:41|
4, 5-Dimethoxycanthin-6-one 998Amyloid (1-42) human TFA suggesting that AMG 337 has4,5 Dimethoxycanthin 6 one is a potent and uncompetitive inhibitor of CYP1A2 mediated phenacetin O deethylation with an IC50 value of 1. 7M and a Ki value of 2. 6 M. 4,5 Dimethoxycanthin 6 one, as an alkaloid, is isolated from the wood of Picrasma quassioides BENNET (Simaroubaceae). Product information CAS Number: 18110 87 7 Molecular Weight: 280. 28 Formula: C16H12N2O3 Chemical Name: 3,4 dimethoxy 1,6 diazatetracyclo[7. 6. 1. 0,. 0,]hexadeca