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AZ3451 is a potent antagonist of protease-activated receptor 2 (PAR2) that binds to a remote allosteric site outside the helical bundle with IC50 of 23 nM
NS 1738 shows comparable efficacy and potency at the rat α7 nAChR (EC50=3
PubMed PMID: 22129763
65(2):159-71
Hollenbach SJ
Mephenesin Catalog No.:M20902-C AZ3451 is a potent antagonistMephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant. Target: NMDA receptor Product information CAS Number: 59 47 2 Molecular Weight: 182. 22 Formula: C10H14O3 Chemical Name: 3 (2 methylphenoxy)propane 1,2 diol Smiles: CC1=CC=CC=C1OCC(O)CO InChiKey: JWDYCNIAQWPBHD UHFFFAOYSA N InChi: InChI=1S C10H14O3 c1 8 4 2 3 5 10(8)13 7 9(12)6 11 h2 5,9,11 12H,6 7H2,1H3 Technical Data Appearance: Solid Power Purity: 98% (or refer to the
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