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and it strongly blocks VEGF induced VEGFR2 phosphorylation in HEK293KDR cells and CSF1 stimulated CSF1R phosphorylation in RAW264
InChi: InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10
InChiKey: VSZGPKBBMSAYNT-RRFJBIMHSA-N
Propargyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs
InChi: InChI=1S/C23H17FN6O
Alisol B 23-acetate PEG1-C2-Boc and it strongly blocks VEGFAlisol B 23 acetate (23 Acetylalismol B), a natural triterpenoid, produces protective effects against EE induced cholestasis, due to FXR mediated gene regulation. IC50 Value: Target: Anti hepatotoxic natural product. In vitro: Alisol B 23 acetate has an effect on FXR activation in a dose dependent manner using luciferase reporter assay in HepG2 cells . In vivo: In alisol B 23 acetate treated mice, the changes in transporters and enzymes, as well as
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