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PK68 Y-100635 (maleate salt) Chemical Name: 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide

SKU: 56543727217

4.6
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Description

Chemical Name: 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide

all times)

CAS Number: 1228013-15-7

Formula: C64H109N19O24S

60 and 80 μM

PK68 Y-100635 (maleate salt) Chemical Name: 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamidePK68 is a potent and selective type II inhibitor of receptor interacting kinase 1 (RIPK1) with an IC50 of ~90 nM, displays inhibition of RIPK1 dependent necroptosis. PK68 powerfully ameliorates TNF induced systemic inflammatory response syndrome, and with great potential for use in the treatment of inflammatory disorders and cancer metastasis. Product information CAS Number: 2173556 69 7 Molecular Weight: 424. 52 Formula: C22H24N4O3S Chemical Name:

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