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3S)-2-(4-chlorophenyl)-1-(1
Mitochonic acid 5 (MA-5)
it does not influence 11β-HSD2expression in airway epithelial cells
InChi: InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4
19(5): 490-496
UMI-77 locitral 3S)-2-(4-chlorophenyl)-1-(1UMI 77 is a selective Mcl 1 inhibitor, which shows high binding affinity to Mcl 1 (IC50=0. 31 M). UMI 77 binds to the BH3 binding groove of Mcl 1 with Ki of 490 nM, showing selectivity over other members of anti apoptotic Bcl 2 members. Product information CAS Number: 518303 20 3 Molecular Weight: 468. 34 Formula: C18H14BrNO5S2 Chemical Name: 2 {[4 (4 bromobenzenesulfonamido) 1 hydroxynaphthalen 2 yl]sulfanyl}acetic acid Smiles:
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