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is a drug of the gliflozin class or subtype 2 sodium-glucose transport (SGLT-2) inhibitors used for the treatment of type 2 diabetes
Epub 2013 Jul 19
2015 Jan 3
14(5):959-965
InChi: InChI=1S/C18H17N3O4S/c1-25-15-8-10-16(11-9-15)26(23
CVT-10216 - CAS# 1005334-57-5 Catalog No.:M6674-2 is a drug of theCVT 10216, CAS No. 1005334 57 5, is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively). CVT 10216 increases acetaldehyde after alcohol gavage and inhibits 2 bottle choice alcohol intake in heavy drinking rodents, including deprivation induced drinking. Moreover, CVT 10216 also prevents operant self administration and eliminates cue induced reinstatement of
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