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25-fold greater sensitivity observed for cells with VHL deficiency compared to wild-type (VHL+)
Bisindolylmaleimide VIII enhances DR5-mediated apoptosis through the MKK4/JNK/p38 kinase and the mitochondrial pathways
and it is converted to uridine for use in the pyrimidine salvage pathway predominantly in liver
Formula: C34H44N2O9
Formula: C23H18N2O2
11-Keto-beta-boswellic acid Catalog No.:M14933-2 25-fold greater sensitivity observed for11 Keto beta boswellic acid (11 Keto boswellic acid) is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense. 11 Keto beta boswellic acid has the anti inflammatory activity is primarily due to inhibit 5 lipoxygenase (5 LOX) and subsequent leukotriene and nuclear factor kappa B (NF B) activation and tumor necrosis factor alpha generation production. Product information
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