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Samuraciclib hydrochloride rofen piconol CAS Number: 229305-39-9

SKU: 52387082030

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Description

CAS Number: 229305-39-9

Formula: C25H29N3O6S

the activity of CZ415 against the human cardiac ion channel hERG is assessed in a whole-cell patch-clamp assay in HEK293 cells resulting in an IC50 of 48 μM

Smiles: CC1C=C(C)NC(=O)C=1CN1CCC2=C(C(Cl)=C(C=C2Cl)C2C(C)=NOC=2C)C1=O

administration to tumor-bearing mice

Samuraciclib hydrochloride rofen piconol CAS Number: 229305-39-9Samuraciclib hydrochloride (CT7001 hydrochloride) is a potent, selective, ATP competitive and orally active CDK7 inhibitor, with an IC50 of 41 nM. Samuraciclib hydrochloride displays 45 , 15 , 230 and 30 fold selectivity over CDK1, CDK2 (IC50 of 578 nM), CDK5 and CDK9, respectively. Samuraciclib hydrochloride inhibits the growth of breast cancer cell lines with GI50 values between 0. 2 0. 3 M. Samuraciclib hydrochloride has anti tumor effects. Product

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