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Minakuchi K
Chemical Name: (2R)-2-[N-benzyl4-(2-fluoroethoxy)benzenesulfonamido]-N-hydroxy-3-methylbutanamide
and dog plasma
every 7 days
InChi: InChI=1S/C47H64N4O12/c1-24-13-12-14-25(2)46(59)49-37-32(23-48-51-20-18-50(19-21-51)31-15-10-11-16-31)41(56)34-35(42(37)57)40(55)29(6)44-36(34)45(58)47(8
24(S)-Hydroxycholesterol h-A01 Minakuchi K24(S) Hydroxycholesterol (24S OHC), the major brain cholesterol metabolite, plays an important role to maintain homeostasis of cholesterol in the brain. 24(S) Hydroxycholesterol (24S OHC) is one of the most efficient endogenous LXR agonist known and is present in the brain and in the circulation at relatively high levels. 24(S) Hydroxycholesterol (24S OHC) is a very potent, direct, and selective positive allosteric modulator of NMDARs with a mechanism
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