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DK419 inhibited the growth of CRC tumor cells in vitro
it is approximately 100-fold selective for GPR40 with respect to GPR120
It has anti-inflammatory effects and is under development as an orally administered drug for the treatment of inflammatory conditions of the lungs such as asthma
Solubility: DMSO: 45 mg/mL(100
The nuclear localization of Nrf2 is inhibited in aortic endothelial cells from mice treated with BIX02189
NS-1619 bitor 1 DK419 inhibited the growth ofNS1619 is a Bkca opener or large conductance Ca2+ activated potassium (BKCa, KCa1. 1) channel activator. NS1619 pretreatment protects against shock induced vascular hyporeactivity through PDZ Rho GEF RhoA Rho kinase pathway in rats. NS1619 modulates calcium homeostasis in muscle cells by inhibiting SERCA. NS1619 decreases myogenic and neurogenic contractions of rat detrusor smooth muscle. Product information CAS Number: 153587 01 0 Molecular Weight:
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