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Upregulation of microRNA‑590 in rheumatoid arthritis promotes apoptosis of bone cells through transforming growth factor‑β1/phosphoinositide 3‑kinase/Akt signaling
InChi: InChI=1S/C18H12ClF3N4O4/c19-12-13-7(1-9(20)14(12)25-3-6(27)4-25)15(28)8(18(29)30)5-26(13)17-11(22)2-10(21)16(23)24-17/h1-2
19(2):421-430
Li/c16-9-5-8(15(24)25)12(6-10(9)17)19-14(23)11-1-2-13(21-20-11)22-4-3-18-7-22
CAS Number: 338967-87-6
MRT68921 dihydrochloride ine (sodium salt pentahydrate) Upregulation of microRNA‑590 in rheumatoidMRT68921 dihydrochloride is a potent inhibitor of ULK1 and ULK2, with IC50 values of 2. 9 nM and 1. 1 nM, respectively. Product information CAS Number: 2080306 21 2 Molecular Weight: 507. 50 Formula: C25H36Cl2N6O Chemical Name: N [3 ({5 cyclopropyl 2 [(2 methyl 1,2,3,4 tetrahydroisoquinolin 6 yl)amino]pyrimidin 4 yl}amino)propyl]cyclobutanecarboxamide; bis(chlorohydrogen) Smiles: Cl. Cl. CN1CC2C=CC(=CC=2CC1)NC1N=C(NCCCNC(=O)C2CCC2)C(=CN=1)C1CC1
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