GSK-3 inhibitor 1 Size:Solid 2 mg with IC50 ~6 nM and

with IC50 ~6 nM and 15 nM for G9a and GLP

with GI50s of 14 μM

Machini WB

M1001 is a weak agonist of hypoxia-inducible factor-2α (HIF-2α) that binds to the HIF-2α PAS-B domain with Kd of 667 nM

Smiles: NC(CCP(O)(O)=O)C(O)=O

GSK-3 inhibitor 1 Size:Solid 2 mg with IC50 ~6 nM andGSK 3 inhibitor 1 is an inhibitor of GSK 3. Product information CAS Number: 603272 51 1 Molecular Weight: 437. 85 Formula: C22H17ClFN5O2 Chemical Name: 3 {6 fluoro 1,10 diazatricyclo[6. 4. 1. 0,]trideca 2,4,6,8(13) tetraen 3 yl} 4 {imidazo[1,2 a]pyridin 3 yl} 2,5 dihydro 1H pyrrole 2,5 dione hydrochloride Smiles: Cl. O=C1NC(=O)C(=C1C1=CN2CCNCC3=CC(F)=CC1=C23)C1=CN=C2C=CC=CN21 InChiKey: CXXAOCQHGIGIBJ UHFFFAOYSA N InChi: InChI=1S C22H16FN5O2. ClH c23