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MI-2 concentrated within human ABC-DLBCL cells and irreversibly inhibited cleavage of MALT1 substrates with EC50 < 1 µM (HBL-1 ~200 nM
Supinoxin interacts with Y593 phosphorylated-p68 and attenuates the nuclear shuttling of β-catenin
131:110650
highly selective and irreversible γ−glutamyl transpeptidase (GGT) inhibitor
2-b]pyridazin-6-amine monoadipate
IACS-13909 Size:Contact [email protected] for quotation MI-2 concentrated within human ABC-DLBCLIACS 13909 is a selective, potent and orally active SHP2 allosteric inhibitor with an IC50 of 15. 7 nM and a Kd of 32 nM. IACS 13909 is more selective for SHP2 than other phosphatases (including SHP1). IACS 13909 has antitumor activities and suppresses MAPK pathway signaling in receptor tyrosine kinases (RTK) dependent cancers. Product information CAS Number: 2160546 07 4 Molecular Weight: 377. 27 Formula: C17H18Cl2N6 Chemical Name: 1 [3 (2,3
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