Pay in 4 interest-free payments of $34.75 Learn more
Ships within 48 hours · Estimated delivery Aug 6 - Aug 11
Hsc70 and Grp7
Discovery of I-BRD9
2015 Aug 25
TAK-875 was used at 1 µM final concentration in various in vitro assays
It is an orally available inhibitor of the epidermal growth factor receptor (EGFR)
GNF7156, β Cell Proliferation Inducer - CAS# 2041071-54-7 la-Ala-Asn-PAB-PNP Hsc70 and Grp7GNF7156, CAS No. 2041071 54 7, is a highly potent and selective small molecule that promotes pancreatic cell proliferation in rodent EC50 ~2. 2 Mand human primary islets (EC50 ~0. 76 M). It acts most likely as a result of combined inhibition of DYRK1A and GSK3B. GNF7156 treated human islets retain functionality in vitro and after transplantation into diabetic mice. Oral dosing of GNF7156 in diabetic mice induces cell proliferation, increases cell mass
US$ 1861.50
US$ 1474.50