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ML314 P-6 Chemical Name: 2-((4-chlorophenyl)sulfonyl)-4-methoxy-1-nitrobenzene

SKU: 47292758076

4.3
USD130.00 USD165.00

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Description

Chemical Name: 2-((4-chlorophenyl)sulfonyl)-4-methoxy-1-nitrobenzene

22)/b12-8-

It is found as an accessory pigment in the chloroplasts of brown algae and most other heterokonts

Smiles: CC(C)(C)S(=O)(=O)C1=CC2=C(NC3C=C4N=CSC4=CC=3)N=CN=C2C=C1OCCO

is a MRCK inhibitor

ML314 P-6 Chemical Name: 2-((4-chlorophenyl)sulfonyl)-4-methoxy-1-nitrobenzeneML 314 is a brain penetrant nonpeptidic arrestin biased ggonist of the neurotensin NTR1 receptor, which exhibits full agonist behavior against NTR1 (EC50 = 2. 0 M) in the primary assay and selectivity against NTR2. The effect of ML314 is blocked by the NTR1 antagonist SR142948A in a dose dependent manner. Unlike peptide based NTR1 agonists, ML314 has no significant response in a Ca2+ mobilization assay and is thus a biased agonist that activates the

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