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DNA-damage checkpoint activation
065 μM and IC50 of 1
3]benzothiazol-2-yl]phenyl}urea dihydrochloride
Solubility: DMSO : ≥ 100 mg/mL (221
Formula: C36H61NaO11
survivin (baculoviral IAP repeat-containing protein 5) (21-28) 3104 DNA-damage checkpoint activationSurvivin (baculoviral inhibitor of apoptosis IAP repeat containing protein 5) is a member of the IAP gene family, which has been implicated in both inhibition of apoptosis and mitosis regulation1. Survivin is one of the most uniformly up regulated genes in tumor tissues compared with healthy tissues2. High survivin expression in the primary tumor is almost invariably associated with poor patient prognosis in many cancer types. Survivin relates to poor
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