FLLL32 xizine dihydrochloride since the channel must open

since the channel must open for the drug to bind inside it

NB-1643 p=0

Smiles: CN1C=C(C2SC(=CC=2C1=O)C(=N)NC1CCS(=O)(=O)CC1)C1=CC(OC)=C(C=C1)OCC(=O)NCCCCNC(=O)COC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

288(13):9408-17

7 nM) and IL-1b induced IL-6 (IC5050=1

FLLL32 xizine dihydrochloride since the channel must openFLLL32, a synthetic analog of curcumina, is a JAK2 STAT3 dual inhibitor with anti tumor activity. FLLL32 can inhibit the induction of STAT3 phosphorylation by IFN and IL 6 in breast cancer cells. Product information CAS Number: 1226895 15 3 Molecular Weight: 464. 55 Formula: C28H32O6 Chemical Name: (2E) 3 (3, 4 dimethoxyphenyl) 1 {1 [(2E) 3 (3, 4 dimethoxyphenyl)prop 2 enoyl]cyclohexyl}prop 2 en 1 one Smiles: COC1=CC( C=C C(=O)C2(CCCCC2)C(=O) C=C