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Aurora kinase inhibitor-2 is a selective and ATP-competitive Aurora kinase inhibitor with IC50s of 310 nM and 240 nM for Aurora A and Aurora B
31)32/h1-10
5-dihydroxy-6-methyl-3-{[(2S
Solubility: DMSO : 2
mediated via JAK2)
SAICAR Size:Contact [email protected] for quotation Aurora kinase inhibitor-2 is aSAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme selective manner, with an EC50 of 0. 3 mM. SAICAR stimulates PKM2 and promotes cancer cell survival in glucose limited conditions. Product information CAS Number: 3031 95 6 Molecular Weight: 454. 28 Formula: C13H19N4O12P Chemical Name: (2S) 2 ({5 amino 1 [(2R,3R,4S,5R) 3,4 dihydroxy 5 [(phosphonooxy)methyl]oxolan 2 yl] 1H
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