3 skin tumors per mouse (tumor multiplicity)
XL765 also inhibits DNA-PK (IC50 = 150 nM) and mTOR (IC50 = 157 nM) but not XL-147 which shows IC50 values of > 15 μM
Chemical Name: 2-(4-{1-[(quinolin-6-yl)methyl]-1H-[1
Laminin (925-933) is a peptide derived from residues 925-933 of the Laminin B1 chain that binds to the laminin receptor
22-45-24-40-23-41-45)33-13-4-28(38)18-34(33)39/h4-13
Biotin-PEG6-NHS ester Catalog No.:M28640-C 3 skin tumors per mouseBiotin PEG6 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2055045 04 8 Molecular Weight: 676. 78 Formula: C29H48N4O12S Chemical Name: 2,5 dioxopyrrolidin 1 yl 1 {5 [(3aS,4S,6aR) 2 oxo hexahydro 1H thieno[3,4 d]imidazol 4 yl]pentanamido} 3,6,9,12,15,18 hexaoxahenicosan 21 oate Smiles: O=C1N[C@H]2CS[C@@H](CCCCC(=O)NCCOCCOCCOCCOCCOCCOCCC(=O)ON3C(=O)CCC3=O)[C@H]2N1 InChiKey: