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a biomarker of CDK8 inhibition
and it also inhibits the activation of Arf6 by its GEFs
AG-13958 (AG-013958)
Formula: C42H82N2O22
InChiKey: OTLZAXXVHHHGDU-WFGJKAKNSA-N
Protein Kinase C Peptide Substrate ol isoflavone a biomarker of CDK8 inhibitionProtein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G protein coupled receptors, tyrosine kinase receptors, or tyrosine kinase coupled receptors. Protein Kinase C Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine,