APS-2-79 modulates KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK (mitogen-activated protein kinase kinase)
Shearer TW
24)/b19-16-
InChi: InChI=1S/C50H62ClN9O8S2/c1-28-31(4)70-49-42(28)43(34-13-15-36(51)16-14-34)55-38(46-58-57-32(5)60(46)49)24-40(62)52-17-18-66-19-20-67-21-22-68-26-41(63)56-45(50(6
guinea pig
Spectinomycin dihydrochloride Catalog No.:M9037-10 APS-2-79 modulates KSR-dependent MAPK signallingSpectinomycin is an antibiotic useful for the treatment of gonorrhea infections. It is given by injection into a muscle. Common side effects include pain at the area of injection, rash, nausea, fever, and trouble sleeping. Product information CAS Number: 21736 83 4 Molecular Weight: 368. 81 Formula: C14H25ClN2O7 Synonym: Trobicin Chemical Name: (1R,3S,5R,8R,10R,11S,12S,13R,14S) 8,12,14 trihydroxy 5 methyl 11,13 bis(methylamino) 2,4,9 trioxatricyclo[8.