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Smiles: CC(=O)C1=CC2C(=O)CC(C)(C)OC=2C=C1
Formula: C28H38O6
Inhibits HLE-induced lung hemorrhage in mice (ID50 = 2
and permitted photolysis of DPNI-GABA to mimic synaptic activation of GABAA receptors
21S)-18-(3-aminopropyl)-12-benzyl-15-[(2R)-butan-2-yl]-3-(carbamoylmethyl)-6-(carboxylatomethyl)-9-[(1H-imidazol-5-yl)methyl]-2
U-44069 Size:Contact [email protected] for quotation Smiles: CC(=O)C1=CC2C(=O)CC(C)(C)OC=2C=C1EC50: 3 M and 54 nM for platelet aggregation and phosphatidate formation in human platelets, respectively U 44069 is a TP receptor agonist. Increased production of vasoconstrictive prostanoids, such as thromboxane A2, contributes to endothelial dysfunction and increased hepatic vascular tone in cirrhosis. Thromboxane A2 induces vasoconstriction via activation of the thromboxane A2 prostaglandin endoperoxide (TP) receptor. In vitro: In a previous