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GO-6976 - CAS# 136194-77-9 10001 AEB071 (sotrastaurin) does not exhibit

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Description

AEB071 (sotrastaurin) does not exhibit toxic effects on human islets in vitro

InChi: InChI=1S/C16H9ClF3NO2/c17-12-3-1-2-11-13(12)21(15(23)14(11)22)8-9-4-6-10(7-5-9)16(18

CAS Number: 1034148-04-3

culminating into cytotoxicity

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

GO-6976 - CAS# 136194-77-9 10001 AEB071 (sotrastaurin) does not exhibitGO 6976, CAS No. 136194 77 9, also known as PD 406976, is a potent inhibitor of neurotrophin receptor intrinsic tyrosine kinase. GO 6976 blocked neurotrophin induced signaling and autophosphorylation of neurotrophin specific tyrosine kinase (Trk) receptors, either Trk B in cortical neurons or Trk A in GT1 1 trk9 cells. Product information CAS Number: 136194 77 9 Molecular Weight: 378. 43 Formula: C24H18N4O Synonym: PD406976 Chemical Name: 3 (13 methyl

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