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Formula: C13H8N6
InChiKey: KPOOEJJPTYXNTN-UHFFFAOYSA-P
Zardaverine exhibits potent and selective antitumor activity against hepatocellular carcinoma both in vitro and in vivo independently of phosphodiesterase inhibition
when added to human plasma
Activation of mTORC1 (indicated by p-S6K1 and p-4E-BP1) and mTORC2 is almost blocked by WAY-600 (100 nM)
Icotinib Hydrochloride - CAS# 1204313-51-8 Size:Solid 10 mg Formula: C13H8N6Icotinib, also known as BPI 2009, is an orally available quinazoline based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib selectively inhibits the wild type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, is upregulated in a variety of cancer cell
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