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Daprodustat 10736 Tomatidine decreases inducible NO synthase

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Description

Tomatidine decreases inducible NO synthase and COX-2 expression through suppression of I-κBα phosphorylation

Pyrogallol (PG) is a reductant that is able to generate free radicals

Formula: C21H36N4O8

CAS Number: 849217-64-7

[Epub ahead of print] PubMed PMID: 30126942

Daprodustat 10736 Tomatidine decreases inducible NO synthaseDaprodustat (GSK1278863) is an orally active hypoxia inducible factor prolyl hydroxylase (HIF PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease. Product information CAS Number: 960539 70 2 Molecular Weight: 393. 43 Formula: C19H27N3O6 Chemical Name: 2 [(1,3 dicyclohexyl 2,4,6 trioxo 1,3 diazinan 5 yl)formamido]acetic acid Smiles: OC(=O)CNC(=O)C1C(=O)N(C2CCCCC2)C(=O)N(C2CCCCC2)C1=O InChiKey: RUEYEZADQJCKGV

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