Thalidomide-NH-PEG8-Ts henolate mofetil Hydrochloride Atglistatin was used at 10

Atglistatin was used at 10 μM final concentration in vitro and in cellular assays

Smiles: CC1(C)[C@H]2CC(=O)[C@]1(CS(O)(=O)=O)CC2

InChiKey: YDQWDHRMZQUTBA-UHFFFAOYSA-N

KDM5B a histone H3K4 demethylase involved in regulation of cell proliferation and stem cell self-renewal and differentiation

Smiles: CC1N=C(NC(=O)C=1CC)SCC(=O)NC1=NC(=CS1)C1=CC=C(C=C1)OC

Thalidomide-NH-PEG8-Ts henolate mofetil Hydrochloride Atglistatin was used at 10Thalidomide NH PEG8 Ts is a synthesized E3 ligase ligand linker conjugate that incorporates the Thalidomide based cereblon ligand and 8 unit PEG linker used in PROTAC technology, such as IDO1 PROTAC degrader (HY 131911). Product information CAS Number: 2488761 07 3 Molecular Weight: 779. 85 Formula: C36H49N3O14S Chemical Name: 23 {[2 (2,6 dioxopiperidin 3 yl) 1,3 dioxo 2,3 dihydro 1H isoindol 4 yl]amino} 3,6,9,12,15,18,21 heptaoxatricosan 1 yl 4