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99570-78-2
18(9):2502-14
but activates only the α7 to any significant extent
90% PEG300
InChiKey: LSPANGZZENHZNJ-UHFFFAOYSA-N
PLX-4720 - CAS# 918505-84-7 60209 99570-78-2PLX 4720, CAS No. 918505 84 7, is a 7 azaindole derivative that inhibits B Raf(V600E) with an IC(50) of 13 nM, defines a class of kinase inhibitor with marked selectivity in both biochemical and cellular assays. PLX 4720 preferentially inhibits the active B Raf(V600E) kinase compared with a broad spectrum of other kinases, and potent cytotoxic effects are also exclusive to cells bearing the V600E allele. Product information CAS Number: 918505 84 7
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