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L002 was administered through IP injection at 500 µg/100 µl twice a week for 3 weeks in xenografts models
Acalabrutinib inhibits purified BTK with an IC50 of 3 nM and an EC50 of 8 nM in a human whole-blood CD69 B cell activation assay
dimerization
Fmoc-Val-Cit-PAB-OH
Foslinanib
WY-14643 - CAS# 50892-23-4 Catalog No.:M6460-2 L002 was administered through IPWY 14643, also known as pirinixic acid, CAS No. 50892 23 4, is a selective PPAR agonist. WY 14643 negatively inhibits NF B transcriptional activity and decreases the inflammatory response in vitro and in vivo. Product information CAS Number: 50892 23 4 Molecular Weight: 323. 80 Formula: C14H14ClN3O2S Synonym: WY 14643 WY 14643 WY14643 Pirinixic Acid Chemical Name: [[4 chloro 6 [(2,3 dimethylphenyl)amino] 2 pyrimidinyl]thio] acetic acid Smiles: