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T-448 hoxymethyl) ethanol 4-dichlorophenyl)piperidin-3-yl]propyl}-4-phenylpiperidin-4-yl)-N-methylacetamide

SKU: 38206105004

4.8
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Description

4-dichlorophenyl)piperidin-3-yl]propyl}-4-phenylpiperidin-4-yl)-N-methylacetamide

Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases

Na/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7

InChiKey: NODGUBIGZKATOM-UHFFFAOYSA-N

InChi: InChI=1S/C144H248N40O35S/c1-73(2)61-105(177-121(195)85(19)157-128(202)97(44-28-35-55-146)170-118(192)82(16)165-139(213)108(64-76(7)8)181-134(208)101(48-32-39-59-150)172-115(189)79(13)161-132(206)103(50-52-113(185)186)174-126(200)94(152)67-91-69-154-95-42-26-25-41-93(91)95)136(210)162-80(14)116(190)168-96(43-27-34-54-145)127(201)156-87(21)123(197)179-107(63-75(5)6)138(212)164-84(18)120(194)173-102(49-33-40-60-151)135(209)183-111(68-92-70-153-72-155-92)142(216)182-109(65-77(9)10)140(214)166-83(17)119(193)171-98(45-29-36-56-147)129(203)158-86(20)122(196)178-106(62-74(3)4)137(211)163-81(15)117(191)169-99(46-30-37-57-148)130(204)159-88(22)124(198)180-110(66-78(11)12)141(215)175-100(47-31-38-58-149)131(205)160-89(23)125(199)184-112(71-220)143(217)176-104(51-53-114(187)188)133(207)167-90(24)144(218)219/h25-26

T-448 hoxymethyl) ethanol 4-dichlorophenyl)piperidin-3-yl]propyl}-4-phenylpiperidin-4-yl)-N-methylacetamideT 448 is a specific, orally active and irreversible inhibitor of lysine specific demethylase 1 (LSD1, an H3K4 demethylase), with an IC50 of 22 nM. T 448 enhances H3K4 methylation in primary cultured rat neurons. Product information CAS Number: 1597426 53 3 Molecular Weight: 444. 50 Formula: C21H24N4O5S Chemical Name: (2E) but 2 enedioic acid; 3 [(1R,2S) 2 (cyclobutylamino)cyclopropyl] N (5 methyl 1,3,4 thiadiazol 2 yl)benzamide Smiles:

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