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AUY-922 (500 nM) in combination with NSC 118218 more effectively induces apoptosis in cells in co-culture than either drug alone
Molecular Weight: 1111
CAS Number: 199113-98-9
InChi: InChI=1S/C26H42N6O12S2/c1-13(2)8-17(26(43)44)32-24(41)15(4-5-20(35)36)30-25(42)18(11-45)29-19(34)10-27-22(39)16(9-21(37)38)31-23(40)14(28-12-33)6-7-46-3/h12-18
4R)-1-[(2S)-2-(3-aminopropanamido)-3
Filanesib TFA menidine phosphate AUY-922 (500 nM) in combinationFilanesib TFA (ARRY 520 TFA) is a selective kinesin spindle protein (KSP) inhibitor, with an IC50 of 6 nM for human KSP. Filanesib TFA induces cell death by apoptosis in vitro. Filanesib TFA has potent anti proliferative activity. Product information CAS Number: 1781834 99 8 Molecular Weight: 534. 50 Formula: C22H23F5N4O4S Chemical Name: (2S) 2 (3 aminopropyl) 5 (2,5 difluorophenyl) N methoxy N methyl 2 phenyl 2,3 dihydro 1,3,4 thiadiazole 3