3-Hydroxy Midostaurin - CAS# 179237-49-1 7895 and k6 = 0

and k6 = 0

2174/1574887112666170406104854

457081-03-7

demonstrating that the loss of hypersensitivity in Trpm3-/- mice is unlikely to be caused by developmental or compensatory mechanisms and suggests that TRPM3 may be a tractable target for inflammatory pain

ML-00253764 (100 µM) decreases cAMP production induced by [NLE4

3-Hydroxy Midostaurin - CAS# 179237-49-1 7895 and k6 = 03 Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS like tyrosine kinase 3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9. 8 M in culture medium and plasma, respectively. 3 Hydroxy Midostaurin is less selective but more cytotoxic than PKC412. Product information CAS Number: 179237 49 1 Molecular Weight: 600. 66 Formula: C36H32N4O5 Chemical Name: N [(2R,4S,5S,7R) 17 hydroxy 5 methoxy 7 methyl 19 oxo