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H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17
MAO-A and MAO-B (IC50 > 10 μM)
1 nM for EP300 HAT
Buchdunger et al (1994) 4
Yamauchi T
RS-127445 hydrochloride Catalog No.:M14905-10 H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17RS 127445 hydrochloride is a selective, high affinity, orally bioavailable 5 HT2B receptor antagonist with a pKi of 9. 5. RS 127445 hydrochloride shows 1000 fold selectivity for this receptor as compared to numerous other receptor and ion channel binding sites. Product information CAS Number: 199864 86 3 Molecular Weight: 317. 79 Formula: C17H17ClFN3 Chemical Name: 4 (4 fluoronaphthalen 1 yl) 6 (propan 2 yl)pyrimidin 2 amine; chlorohydrogen Smiles:
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