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High-Throughput Virtual Screening Identifies Novel N'-(1-Phenylethylidene)-benzohydrazides as Potent
2018-0335OC
Evidence for Clinical Differentiation and Differentiation Syndrome in Patients With Acute Myeloid Leukemia and IDH1 Mutations Treated With the Targeted Mutant IDH1 Inhibitor
the rate-limiting enzyme involved in the conversion of nicotinamide into nicotinamide adenine dinucleotide (NAD)
5 cell line
YM-155 - a survivin inhibitor. CAS# 781661-94-7 0263 High-Throughput Virtual Screening Identifies NovelYM 155, CAS No. 781661 94 7, is a novel survivin suppressant with an IC50 of 0. 54 nM for the inhibition of survivin promoter activity. Sepantronium bromide, also known as YM 155, is a small molecule proapoptotic agent with potential antineoplastic activity. Survivin inhibitor YM155 selectively inhibits survivin expression in tumor cells, resulting in inhibition of survivin antiapoptotic activity (via the extrinsic or intrinsic apoptotic pathways) and
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