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Cerdulatinib preferentially inhibited JAK1 and JAK3 dependent cytokine mediated signaling and functional responses in various cell types
InChi: InChI=1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H
3 and 24 μM for human STING isoforms WT and HAQ
Ki8751 (5 mg/kg) completely inhibits tumor growth without affecting body weight
20-9-5-3-6-10-20)21-11-7-4-8-12-21/h3-12
CFTR corrector 2 diphosphate analog 1 Cerdulatinib preferentially inhibited JAK1 andCFTR corrector 2 is a cystic fibrosis transmembrane conductance corrector (CFTR), extracted from patent US20140274933. Product information CAS Number: 1628416 28 3 Molecular Weight: 486. 49 Formula: C27H23FN4O4 Chemical Name: 2 [7 ethoxy 4 (3 fluorophenyl) 1 oxo 1,2 dihydrophthalazin 2 yl] N methyl N (2 methyl 1,3 benzoxazol 6 yl)acetamide Smiles: CN(C1C=C2OC(C)=NC2=CC=1)C(=O)CN1N=C(C2C=CC(=CC=2C1=O)OCC)C1C=C(F)C=CC=1 InChiKey: XRPSUWYWZUQALB
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