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2016 Oct 10
Lodoxamide Study Group
JUN90152 shows 150-fold selectivity for SMS2 over SMS1 (IC50 of 1000 nM)
Guanidine hydrochloride at low concentrations refolds acid-unfolded apomyoglobin and cytochrome c
Protopine is a novel microtubule stabilizer with anticancer activity in HRPC cells through apoptotic pathway by modulating Cdk1 activity and Bcl-2 family of proteins[2]
Avatrombopag Catalog No.:M11396-10 2016 Oct 10Avatrombopag, also known as AKR 501, YM477, AS 1670542 or E5501, is a novel orally active thrombopoietin (TPO) receptor agonist. AKR 501 specifically targeted the TPO receptor and stimulated megakaryocytopoiesis throughout the development and maturation of megakaryocytes just as rhTPO did. AKR 501 may be useful in the treatment of patients with thrombocytopenia. Avatrombopag was first approved in 2018. Product information CAS Number: 570406 98 3
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