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InChi: InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3
thereby blocking the interaction of TRAF6 with Ubc13
InChiKey: XUFQPHANEAPEMJ-UHFFFAOYSA-N
Manidipine decreases the blood pressure to the normotensive level between 1 hour and 3 hours after Manidipine is administered
expressed as a percentage of luminescence units from solvent (DMSO)-treated cells at the same time intervals
PF-05085727 at) TFA InChi: InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3PF 05085727 is a potent, selective and brain penetrant inhibitor of cGMP dependent PDE2A (IC50=2 nM). PF 05085727 inhibits PDE2A >4,000 fold selectivity over PDE1 and PDE3 11. Product information CAS Number: 1415637 72 7 Molecular Weight: 413. 40 Formula: C20H18F3N7 Chemical Name: 4 [4 (azetidin 1 yl) 1 methyl 1H pyrazolo[3,4 d]pyrimidin 3 yl] 1 methyl 5 [4 (trifluoromethyl)phenyl] 1H pyrazole Smiles:
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