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Smiles: CN1CCN(CC1)C1=C(F)C2=C(C(N)=C1F)C(=O)C(=CN2C1CC1)C(O)=O
Treatment of hepatocytes with EX229 (991) alone results in a slight increase in the phosphorylation of AMPK and RAPTOR only at 0
the combination of a GSK3 inhibitor (CHIR99021
61 μmol/min after SQ28603 and vehicle respectively) and by 77% in the lungs (0
CAS Number: 115966-68-2
BAY 59-9435 as G12C inhibitor 3 Smiles: CN1CCN(CC1)C1=C(F)C2=C(C(N)=C1F)C(=O)C(=CN2C1CC1)C(O)=OBAY 59 9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0. 023 M. Product information CAS Number: 654059 21 9 Molecular Weight: 266. 34 Formula: C14H22N2O3 Chemical Name: 3 methyl 2 [(3S) 3 methylpiperidine 1 carbonyl] 4 (propan 2 yl) 2,5 dihydro 1,2 oxazol 5 one Smiles: CC1=C(C(C)C)C(=O)ON1C(=O)N1CCC[C@H](C)C1 InChiKey: XWESKOHENXWEAX JTQLQIEISA N InChi: InChI=1S C14H22N2O3 c1 9(2)12 11(4)16(19
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