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Genipin Size:Solid 10 mg a novel plasminogen activator inhibitor-1

SKU: 32624502882

4.5
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Description

a novel plasminogen activator inhibitor-1 inhibitor

was first reported in Journal of Medicinal Chemistry (2009)

also known as PORCN Inhibitor III and Wnt Pathway Inhibitor XIX

streptozocin causes little myelosuppression

Smiles: CC(C)(O)[C@H]1CC[C@](C)(O1)[C@H]1[C@@H](O)C[C@@]2(C)[C@@H]3C[C@H](O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@@H]4[C@]5(C[C@]53CC[C@@]21C)CC[C@H](O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)C4(C)C

Genipin Size:Solid 10 mg a novel plasminogen activator inhibitor-1Genipin is a natural compound isolated from Gardenis jasminoides Ellis fruits, was originally identified as a protein cross linking agent. Genipin ameliorates hypertension induced renal damage via the angiotensin II TLR MyD88 MAPK pathway. genipin shows therapeutic potential for central neurodegenerative diseases. IRE1 inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma. Product

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